Biochem/physiol Actions

Primary TargetInvolved in vasodilator actions of kinins such as bradykinin

Cell permeable: no

Reversible: no

Product does not compete with ATP.

Target IC₅₀: 25-50 µM inhibiting MAP kinase in rat mesangial cells

General description

Involved in vasodilator actions of kinins such as bradykinin. Inhibits MAP kinase in rat mesangial cells (IC₅₀ = 25-50 µM). Regulates the activity of adenylate cyclase via G-protein coupled receptors.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Li, X., et al. 1995. Am. J. Physiol.269, C986.Kessler, W., et al. 1992. Exp. Brain Res.91, 467.

Packaging

1 mg in Plastic ampoule

Warning

Toxicity: Harmful (C)